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ScriptManager is a class and a control in Ajax. The ScriptManager class in ASP.NET manages Ajax Script Libraries, partial page rendering functionality and client proxy class generation by creating an instance of the Ajax runtime on the browser, for web applications and services. The ScriptManager control (that we may drag on a web form) is actually an instance of the ScriptManager class that we put on a web page. The ScriptManager manages all the ASP.NET Ajax controls on a web page.